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Anti-Infective Medications

Antibiotics

Medication (Generic Name)IndicationsCommon Side EffectsAdverse EffectsNursing Considerations
Ciprofloxacin (Fluoroquinolone)Bacterial InfectionsNausea, diarrhea, headacheTendon rupture, central nervous system effects, Clostridium difficile infectionEducate on the importance of completing the full course of antibiotics.
Amoxicillin (Penicillin Antibiotic)Bacterial InfectionsRash, diarrhea, abdominal painAllergic reactions, severe diarrhea, anaphylaxisMonitor for signs of allergic reactions; educate on proper use.
Doxycycline (Tetracycline Antibiotic)Bacterial InfectionsGI upset, photosensitivityTooth discoloration, hepatotoxicity, esophageal ulcersAdminister with food to reduce GI upset; avoid lying down for 30 minutes.
Vancomycin (Glycopeptide Antibiotic)Severe Bacterial InfectionsRed man syndrome, nephrotoxicityOtotoxicity, renal dysfunction, C. difficile infectionAdminister at a controlled rate; monitor renal function.

Medication (Generic Name)IndicationsCommon Side EffectsAdverse EffectsNursing Considerations
Azithromycin (Macrolide Antibiotic)Bacterial InfectionsNausea, diarrhea, abdominal painCardiac arrhythmias, hepatotoxicity, allergic reactionsEducate on potential drug interactions and follow-up testing.
Clindamycin (Lincosamide Antibiotic)Anaerobic Bacterial InfectionsNausea, metallic taste, diarrheaC. difficile infection, Stevens-Johnson syndromeEducate on the importance of completing the full course of antibiotics.
Cephalexin (Cephalosporin Antibiotic)Bacterial InfectionsGI upset, skin rash, headacheAllergic reactions, blood disorders, renal dysfunctionMonitor renal function; assess for signs of allergic reactions.
Linezolid (Oxazolidinone Antibiotic)Gram-Positive Bacterial InfectionsDiarrhea, headache, nauseaMyelosuppression, serotonin syndrome, optic neuropathyMonitor blood counts; educate on serotonin syndrome symptoms.

 

 

Antivirals

Medication (Generic Name)IndicationsCommon Side EffectsAdverse EffectsNursing Considerations
Oseltamivir (Antiviral)InfluenzaNausea, vomiting, headacheNeuropsychiatric events, anaphylaxis, severe skin reactionsAdminister within 48 hours of symptom onset for influenza treatment.
Acyclovir (Antiviral)Herpes Infections, ShinglesNausea, headache, rashRenal dysfunction, hallucinations, seizuresEncourage fluid intake; assess for neurologic symptoms.
Valacyclovir (Antiviral)Herpes Infections, ShinglesNausea, headache, abdominal painThrombotic thrombocytopenic purpura, renal dysfunctionEducate on the importance of adherence to the prescribed regimen.
Lopinavir/Ritonavir (HIV Protease Inhibitors)HIV InfectionDiarrhea, nausea, elevated lipidsCardiac arrhythmias, pancreatitis, immune reconstitution syndromeMonitor for drug interactions and follow-up testing.

Medication (Generic Name)IndicationsCommon Side EffectsAdverse EffectsNursing Considerations
Ganciclovir (Antiviral)Cytomegalovirus InfectionsNausea, vomiting, diarrheaBone marrow suppression, renal dysfunction, neurologic effectsMonitor blood counts and renal function; assess for neurologic symptoms.
Ritonavir (HIV Protease Inhibitor)HIV InfectionNausea, diarrhea, fatigueCardiac arrhythmias, hepatotoxicity, pancreatitisMonitor liver function and educate on potential drug interactions.
Foscarnet (Antiviral)Cytomegalovirus, Herpes InfectionsNausea, renal dysfunction, seizuresElectrolyte imbalances, renal dysfunction, bone disordersMonitor renal function and electrolyte levels; assess for seizures.
Sofosbuvir/Ledipasvir (Direct-Acting Antiviral)Hepatitis C InfectionFatigue, headache, diarrheaHepatic decompensation, severe skin reactions, anemiaMonitor liver function and educate on potential side effects.

 

 

Antifungals

Medication (Generic Name)IndicationsCommon Side EffectsAdverse EffectsNursing Considerations
Fluconazole (Antifungal)Fungal InfectionsNausea, headache, abdominal painLiver dysfunction, QT prolongation, allergic reactionsAssess for potential drug interactions; monitor liver function.
Nystatin (Antifungal)Candidiasis (Oral, Skin, GI Tract)Oral irritation, diarrheaGastrointestinal upset, skin rash, anaphylaxisEducate on proper administration; monitor for side effects.
Terbinafine (Antifungal)Fungal Nail InfectionsGI upset, headache, skin rashHepatotoxicity, blood disorders, severe skin reactionsMonitor liver function; assess for blood count changes.
Amphotericin B (Antifungal)Severe Fungal InfectionsFever, chills, anemiaRenal dysfunction, hypotension, neurologic effectsAdminister with caution and monitor for infusion reactions.

Medication (Generic Name)IndicationsCommon Side EffectsAdverse EffectsNursing Considerations
Voriconazole (Antifungal)Fungal InfectionsVisual disturbances, nauseaHepatotoxicity, neurologic effects, severe skin reactionsMonitor liver function and educate on visual side effects.
Ketoconazole (Antifungal)Fungal Infections, Cushing's SyndromeNausea, abdominal pain, headacheHepatotoxicity, QT prolongation, adrenal suppressionMonitor liver function; assess for adrenal suppression.
Griseofulvin (Antifungal)Dermatophyte InfectionsGI upset, headache, photosensitivityHepatotoxicity, blood disorders, hypersensitivity reactionsAdminister with high-fat meals; educate on potential skin reactions.
Micafungin (Echinocandin Antifungal)Fungal InfectionsFever, abdominal pain, rashLiver dysfunction, hypersensitivity reactions, electrolyte imbalancesMonitor liver function and electrolyte levels; assess for allergic reactions.

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