Gastrointestinal Medications

Medication (Generic
Name)
IndicationsCommon
Side Effects
Adverse
Effects
Nursing
Considerations
Omeprazole (Proton
Pump
Inhibitor)
GERD,
Ulcers,
Zollinger
Ellison
Syndrome
Headache,
abdominal
pain,
diarrhea
Risk of C.
difficile
infection,
fractures,
hypomagnesemia
Administer before.
meals.
monitor
magnesium levels.
educate on long-term.
use.
Ranitidine
(H2
Blocker)
GERD,
Ulcers,
Heartburn
Headache,
dizziness,
constipation
Hepatitis,
thrombocytopenia,
confusion
Assess liver function.
monitor
platelet
count.
educate on potential.
interactions.
Metoclopramide
(Prokinetic)
Gastroparesis, Nausea,
Vomiting
Drowsiness, restlessness, diarrheaExtrapyramidal
symptoms, tardive
dyskinesia
Use for
short-term; monitor for movement.
disorders.
caution with CNS effects.
Docusate
Sodium
(Stool
Softener)
ConstipationAbdominal
cramps,
diarrhea
Electrolyte
imbalances, dependence
Promote
dietary fiber and fluid
intake.
educate on long-term.
use.
Loperamide (Antidiarrheal)DiarrheaDizziness,
constipation
Cardiac
arrhythmias, toxic
megacolon
Caution in
patients with severe
infections.
monitor for dehydration.
Sucralfate (Mucosal
Protectant)
Peptic
Ulcers
Constipation, dry mouthAluminum
toxicity,
hypersensitivity
reactions
Administer on an empty stomach.
separate
from other
medications.
Medication (Generic
Name)
IndicationsCommon
Side Effects
Adverse
Effects
Nursing
Considerations
Laxatives
(e.g.,
Senna)
ConstipationAbdominal
cramps,
diarrhea
Electrolyte
imbalances, dependence
Encourage
dietary and fluid intake; use short.
term.
monitor for dehydration.
Ondansetron
(Antiemetic)
Nausea,
Vomiting
Headache,
constipation, fatigue
QT
prolongation, serotonin
syndrome
Assess ECG for QT
prolongation; monitor for signs of
serotonin
syndrome.
Simethicone
(Antiflatulent)
Gas and
Bloating
No
significant
side effects
Rare
hypersensitivity
reactions
Educate on proper.
administration; generally considered safe.
Psyllium
(Bulk
Forming
Laxative)
Constipation, Irritable
Bowel
Syndrome
Abdominal
cramps,
diarrhea
Risk of
choking,
bowel
obstruction
Administer with
adequate
fluids.
educate on appropriate use.
Bismuth
Subsalicylate
(Antidiarrheal)
Diarrhea,
Upset
Stomach
Darkening of tongue and stoolReye's
syndrome
(rare),
salicylate
toxicity
Educate on use in
children.
avoid in
certain
populations (e.g., aspirin allergy).
Pancrealipase
(Pancreatic Enzyme)
Pancreatic
Insufficiency
Abdominal
pain,
diarrhea,
nausea
Allergic
reactions,
hyperuricemia
Administer with meals; monitor for hypersensitivity; assess uric acid.
levels.

Otito-Umoren